Microsoft 365 is a suite, not one application
Microsoft 365 spans office editing (Word, Excel, PowerPoint), communication (Outlook, Exchange, Teams), storage and knowledge (OneDrive, SharePoint), and collaboration (Office Online, shared calendars, Forms). No project here replaces every layer; a realistic open-source setup combines multiple tools.
Replacing Word, Excel, and PowerPoint
ONLYOFFICE Docs focuses on browser-based editing and compatibility with Microsoft Office formats. LibreOffice provides a mature offline desktop suite. Collabora Online brings LibreOffice technology to collaborative browser-based editing. CryptPad prioritizes privacy and encryption, with less emphasis on Office file compatibility.
Replacing Outlook and Exchange
Tuta is the email, calendar, and contacts option in this comparison. It provides hosted encrypted mail and clients but not a complete publicly self-hostable server stack. Organizations requiring self-hosted mail infrastructure need a dedicated mail server in addition to an office suite.
Replacing OneDrive and SharePoint
Papra covers document management and archiving, but it is not a complete file-sync or collaboration platform. CryptPad includes encrypted file storage alongside collaborative documents. A broader migration may pair an office editor with a file platform such as Nextcloud.
Desktop or browser-based office
LibreOffice is primarily desktop software, making it a fit for offline access, local files, and no-account use. ONLYOFFICE Docs, Collabora Online, and CryptPad emphasize browser-based collaboration and centralized editing, which requires server infrastructure.
Privacy, encryption, and data sovereignty
CryptPad encrypts documents in the browser before sending them to the server. Tuta applies a similar privacy-first approach to email, calendar, and contacts. LibreOffice works locally by default. Self-hosting ONLYOFFICE or Collabora gives infrastructure control, but not the same zero-knowledge document model as CryptPad.
Building a broader replacement stack
A more complete deployment could combine Nextcloud for files, calendar, contacts, and collaboration; ONLYOFFICE Docs or Collabora Online for office editing; a dedicated mail server or encrypted provider for email; and Matrix or another collaboration platform for messaging and calls. This provides more infrastructure control but requires operating multiple services.