Important: different kinds of products
Macro is an AI workspace that includes an email client, Inbox Zero is an AI layer that works alongside Gmail or Outlook rather than replacing your client, Tuta is an encrypted email service with its own accounts, and Twake Mail is a JMAP email platform with a client and a backend. Choose by whether you want a client, a layer, or a whole mail service.
Closest to Superhuman
Macro is the closest to a fast, keyboard-driven client, with a multi-account unified inbox, keyboard shortcuts, shared inboxes, and AI agents. Inbox Zero adds AI-drafted replies, bulk unsubscribe, cold email blocking, attachment filing, and analytics on top of Gmail or Outlook, with paid plans from $18 per user per month and self-hosting available.
Important: Tuta is only partly open source
Tuta's client applications are open source under GPL-3.0, but the complete mail service infrastructure is not offered as a public self-hostable stack. It is a hosted service, and it has no AI productivity features comparable to Superhuman's.
License details
Macro, Inbox Zero, and Twake Mail are AGPL-3.0, and Tuta's clients are GPL-3.0.
Maintenance status
Macro, Inbox Zero, Tuta, and Twake Mail all had commits within days of this update. Twake Mail has a small community, with about 650 stars on its client repository.